于文力
[摘要]意图 探討液基薄层细胞学以及活检病理在前期宫颈癌及宫颈上皮内病变筛查中的临床使用价值。办法 选取2008年1月～2014年12月在我院承受宫颈癌筛查的女人作为研讨目标，其间9000例施行液基薄层细胞学查看，891例施行术前活检病理确诊，调查两种办法的确诊成果，并以终究临床确诊成果为根据，剖析两种办法的确诊准确率。成果 9000例承受液基薄层细胞学筛查的女人中，根据细胞学与组织学确诊能够相差一级的准则，低度鳞状上皮内病变（LSIL）、宫颈癌前病变（HSIL）以及鳞状细胞癌（SCC）与终究病理确诊成果的契合率分别为31.9%（375/1174）、83.8%（155/185）、100.0%（65/65）；91例承受活检病理确诊的女人中，CIN 1级、CIN 2级、CIN 3级、SCC与终究病理确诊成果的契合率分别为42.8%（80/187）、61.4%（285/464）、71.3%（132/185）、100.0%（65/65），跟着分级的升高，确诊契合率相应升高，且各组成果比较，差异有统计学含义（P<0.05）。定论 联合使用液基薄层细胞学和活检病理的手法对前期宫颈癌及宫颈上皮内病变进行确诊，有利于进步患者的确诊作用，能够为其前期医治供给牢靠根据。
[关键词]液基薄层细胞学；活检病理；前期宫颈癌；宫颈上皮内病变；确诊
[中图分类号] R737.33 [文献标识码] A [文章编号] 1674-4721（2016）12（a）-0145-03
Clinical application value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions
YU Wen-li
Maternal and Child Health Care Hospital of Liaoning Province，Shenyang 110005，China
[Abstract]Objective To explore the clinical application value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions.Methods Women with cervical cancer screening from January 2008 to December 2014 in our hospital were selected as research subjects，9000 cases were given liquid based cytology test，891 cases were diagnosed by biopsy pathology before operation，and the diagnosis results of the two methods were observed，finally，based on the final clinical diagnosis results，the diagnostic accuracy of the two methods was analyzed.Results 9000 patients who underwent liquid thin-layer cytology screening of women，according to the principle of cytology and histology diagnosis could differ level，LSIL，HSIL and SCC and final pathological diagnosis coincidence rate was 31.9% （375/1174），83.8% （155/185），100.0% （65/65）.91 patients who underwent biopsy pathologic diagnosis of women，CIN 1，CIN 2，CIN 3 stage，SCC and final pathological diagnosis coincidence rate was 42.8% （80/187），61.4% （285/464），71.3% （132/185），100.0% （65/65），with the increase of classification，the diagnostic accuracy was increased，and there was significant difference in the results among each group （P<0.05）.Conclusion The combination of liquid based cytology and biopsy pathology is a method for the diagnosis of early stage of cervical cancer and cervical intraepithelial lesions，it is beneficial to improve the diagnostic efficiency and can provide a reliable basis for early treatment.
[Key words]Liquid thin-layer cytology；Biopsy pathology；Early cervical cancer；Cervical intraepithelial lesions；Diagnosis
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